Endocrine Abstracts

Introduction: TSH-secreting pituitary adenomas are rare pituitary functioning tumors accounting for <2% of the pituitary adenomas. Their association to meningiomas is a very rare condition.We report a case of 55-year-old woman who had multinodular goiter with mild symptoms of hyperthyroidism. Blood tests showed inappropriate secretion of TSH and magnetic resonance imaging (MRI) revealed a pituitary tumor with maximum diameter of 13 mm that was extirp...

Introduction: Phaeochromocytoma and Cushing syndrome are two uncommon endocrine conditions. The association of these two conditions is very rare and not well elucidated. We report an association of a phaeochromocytoma with an ACTH-dependant Cushing syndrome.Case report: A 32-years-old female patient was admitted in the endocrine department for paroxysmal hypertension diagnosed in the immediate post partum period. She reported sweating and palpitation cri...

Introduction: Hyperprolactinemia is a common endocrine condition causing galactorrhoea. Breast abscess is a frequent complication of the post partum period and breast feeding but it rarely occurs out of these two situations. We report the case of a patient presenting with tumoural hyperprolactinaemia associated with a breast abscess.Case report: A 34 years-old patient presented with galactorrhoea, spaniomenorrhoea and headache for six months. She had not...

Cushing disease (CD) is a rare affection due to an ACTH secreting pituitary adenoma with a hypercorticism as main consequence.The aim of this study was to assess glucose tolerance anomalies in CD.Patients: Twenty-one patients with a diagnosed CD were included; The majority of them (77.3%; n=17) were female. Mean age was 34.2 (19–54 years) and mean BMI 31.9 kg/m2 (25.9–43.7). Mean progression period of ...

Achieving glycemic targets is crucial in the management of diabetes mellitus. Insulin is the most effective hypoglycemic treatment for diabetes but its use can be associated with a risk of hypoglycemia.The aim of this study is to specify risk factors of hypoglycemia in insulin-treated patients.Patients and methods: This transversal study included 69 patients. They were females in 49.4% of cases (n=41). Mean age was 52 year...

Prolactinoma is a pituitary adenoma producing prolactin. Central hypogonadism is a major consequence of prolactinoma leading, in women, to menstrual troubles and infertility. The aim of this study was to specify gynecological characteristics of prolactinomas.Patients: This retrospective study included 28 female patients with prolactinoma. Mean age at diagnosis was 35.46 years (ext: 20–78). Mean serum prolactin level was 3442.4 ng/ml (ext: 31.9–...

Introduction: Generously supported by IPSEN)-->Prolactinoma is the commonest pituitary adenoma. The aim of this study was to compare clinical, biological and radiological characteristics in microprolactinoma and macroprolactinoma.Patients: This retrospective study included 33 patients with prolactinoma. The tumor was a microadenoma (<1 cm) in 27.3% (n=9) and a macroadenoma in 72.7% (n=24) ...

Sheehan syndrome is a global or partial pituitary defect occurring after an obstetrical haemorrhage.The aim of this study is to describe metabolic complications in 46 consecutive patients with Sheehan syndrome and to determine correlations between these complications and the clinical, hormonal and therapeutic aspects of this syndrome.All patients have had a physical examination: weight measurement, body mass index (BMI) determinati...